Investigating acute hepatitis of unknown origin in children

What causes hepatitis?

Adenovirus infection in children

The hepatitis outbreak

  • Adenovirus has been detected in at least 74 out of 169 cases.
  • In England and Scotland, 75.5% and 50% of cases were positive for adenovirus, respectively.
  • Subtyping of 11 cases from the U.K. confirmed the presence of adenovirus F41.
  • SARS-CoV-2 was detected in 20 cases.
  • Adenovirus and SARS-CoV-2 coinfection was detected in 19 cases.

The outbreak investigation process

The current working hypotheses

Investigation updates

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